研究業績

李正花

原著論文

  1. Li, Z., Zhao, G., Shen, J., Araki, K., Haruna, K., Inoue, S., Wang, J., Yamamura, K. Enhanced expression of human cDNA by phosphoglycerate kinase promoter-puromycin cassette　in the mouse transthyretin locus. Transgenic Res. 20(1): 191-200, 2011.
  2. Murakami, T., Ohsawa, Y., Li, Z., Yamamura, K., Sunada, Y. The transthyretin gene is expressed in Schwann cells of peripheral nerves. Brain research. 1348: 222-5, 2010.
  3. Jin, S., Zhao, G., Li, Z., Nishimoto, Y., Isohama, Y., Shen, J., Ito, T., Takeya, M., Araki, K., He, P. and Yamamura, K. Age-related pulmonary emphysema in mice lacking a/b hydrolase domain containing 2 gene. Biochem. Biophys. Res. Commun. 380(2): 419-24, 2009.
  4. Tang, H., Araki, K., Ohkido, M., Murakami, Y., Matsufuji, S., Li, Z., Yamamura, K. Role of ornithine decarboxylase antizyme inhibitor in vivo. Genes to Cells. 14(1): 79-87, 2009.
  5. Zhao, G., Li, Z., Araki, K., Haruna, K., Yamaguchi, K., Araki, M., Takeya, M., Ando, Y., Yamamura, K. Inconsistency between hepatic expression and serum concentration of transthyretin in mice humanized at the transthyretin locus. Genes to Cells. 13(12): 1257-68, 2008.
  6. Inoue, S., Ohta, M., Li, Z., Zhao, G., Takaoka, Y., Sakashita, N., Miyakawa, K., Takada,K., Tei, H., Suzuki, M., Masuoka, M., Sakaki, Y., Takahashi, K., Yamamura, K. Specific pathogen free conditions prevent transthyretin amyloidosis in mouse models. Transgenic Research. 17(5): 817-26,2008.
  7. Tang, H., Araki, K., Li, Z., Yamamura, K. Characterization of Ayu17-449 gene expression and resultant kidney pathology in a knockout mouse model. Transgenic Research. 17(4): 599-608, 2008
  8. Chen, H., Li, Z., Haruna, K., Li, Z., Li, Z., Semba, K., Araki, M., Yamamura, K., Araki,K. Early pre-implantation lethality in mice carrying truncated mutation in the RNA polymerase 1-2 gene. Biochem Biophys Res Commun. 365(4): 636-42, 2008.
  9. Yamamura, K., Li, Z., Oike, Y. Patho-physiology of myelin deficient mice. Proceedings of the Japanese Society of Animal Models for Human Diseases. 22: 47-53, 2006.
  10. Li, Z., Takakura , N., Oike, Y., Imanaka, T., Araki, K., Suda, T., Kaname, T., Kondo, T., Abe, K., Yamamura, K. Defective smooth muscle development in qkI-deficient mice. Development Growth and Differentiation. 45(5-6): 449-62, 2003.

学会発表

  1. Li, Z., Araki, K., Yamamura, K.: Production of Optimum Humanized Mouse Model for Familial Amyloidotic Polyneuropathy. Mouse genetics 2011. June 22-25. 2011. Washington, D.C.(Omni Shoreham Hotel)
  2. 李 正花, 荒木喜美, 作村由美, 山村研一: 可変型相同組換え法によるTtrおよびRbp遺伝子座のダブルヒト化マウスの作製.第34回日本分子生物学会年会， 2011.12.13-16，横浜（パシフィコ横浜）
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